Anti-Diabetic Effects of Leucas URTICAEFOLIA –HAM. in STZ-Induced Diabetic Rats

Main Article Content

J. John Wesley
A. Anton Smith
N. Balakrishnan

Abstract

Aims/hypothesis The main objective of this study is to explore the anti-diabetic effects of Leucas Urticaefolia (LU) in STZ-induced diabetic rats.


Methods In this research, we executed in vivo tests on a diabetic Wistar rat model. The studies were carried out, and we orally administered a LU extract and a control medication to streptozotocin (STZ)-induced diabetic rats to assess their anti-diabetic properties.


Results We discovered that a LU extract at a therapeutic dose of 400 mg/kg/body weight had a substantial effect on insulin reduction in STZ-induced rats as compared with the control group (P<0.001). Our histology results also revealed that the extract significantly improved pancreatic and liver histopathology.


Conclusion/ interpretation In vivo investigations demonstrated that LU has an anti-diabetic effect in STZ-induced diabetic rats.

Article Details

How to Cite
J. John Wesley, A. Anton Smith, & N. Balakrishnan. (2022). Anti-Diabetic Effects of Leucas URTICAEFOLIA –HAM. in STZ-Induced Diabetic Rats. Journal of Coastal Life Medicine, 10(3), 352–359. Retrieved from https://jclmm.com/index.php/journal/article/view/204
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