Effect of Mixture of Figs, Dates and Currants on Symptomatology and Changes in Haematology and Biochemical Markers of Iron Deficiency Anaemia

Main Article Content

Shah R
Deshpande S V
Kulkarni A
Gujarathi R H


Background: Iron deficiency is a major cause amongst those of anaemias arising due to inadequate nutrition, worldwide. A large number of iron deficiency cases can be prevented with timely, adequate and appropriate intervention. Anaemia is a major health issue in the developing nations including India with over nearly 70% children affected by it. Around 73 million children suffer from varying degrees of anaemia before they attain the age of three. Pāṇḍu, is a disease narated in Āyurveda, is supposed to be the closest ailment entity similar to that of anaemia, symptomatically. IDA can be effectively managed by providing adequate iron substrate or biological iron through diet. Chemical iron preparations present with various unwarranted effects viz. constipation, vomiting, metallic taste, causing deposits of iron in the tissues which might lead to iron toxicity. Iron from biological origin (from plant and animal origin), also known as biological iron or bio-iron can reduce these symptoms and unwarranted effects to a greater extent, it can be readily absorbed by the human body and readily bio-converted into haemoglobin.
Methodology: This interventional study had supplemented iron from dietary origin i.e biological form of iron from dietary sources using a folklore combination of Figs, Black Currants and Dates fruit, which are considered to be a rich source of iron of biological origin, for the management of children suffering from iron deficiency anaemia of mild to moderate grade.

Results and Conclusions: The trial combination was studied on symptomatology and measured on hematological and biochemical markers of iron deficiency anaemia and it was found to have positive effect with reduction in symptoms, on increasing haemoglobin levels, iron level and ferritin levels in the serum and a marked fall in total iron binding capacity.

Article Details

How to Cite
Shah R, Deshpande S V, Kulkarni A, & Gujarathi R H. (2023). Effect of Mixture of Figs, Dates and Currants on Symptomatology and Changes in Haematology and Biochemical Markers of Iron Deficiency Anaemia. Journal of Coastal Life Medicine, 11(2), 668–675. Retrieved from https://jclmm.com/index.php/journal/article/view/1064


Smith RE (March 2010). "The clinical and economic burden of anemia". The American Journal of Managed Care. 16 Suppl Issues: S59–66. PMID 20297873

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. October 2016. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282

Zimmermann MB, Hurrell RF: Nutritional iron deficiency, Lancet 370:511–520, 200

Ashish KC, Rana N, Malqvist M, et al. Effects of delayed umbilical cord clamping vs early clamping on anemia in infants at 8 and 12 months. JAMA Pediatr. 2017;171(3):264–270

Baker RD, Greer FR, Committee on Nutrition. Clinical report: diagnosis and prevention of iron deficiency and iron deficiency anemia in infants and young children (0-3 years of age). Pediatrics. 2010;126:1040–1050

Berglund SK, Westrup B, Domellöf M. Iron supplementation until 6 months protects marginally low-birth-weight infants from iron deficiency during their first year of life. J Pediatr Gastroenterol Nutr. 2015;60(3):390–395

Fu-Ping Lai , Yao-Jong Yang. The prevalence and characteristics of cow's milk protein allergy in infants and young children with iron deficiency anemia Pediatr Neonatol. 2018 Feb;59(1):48-52. doi: 10.1016/j.pedneo.2017.01.004. Epub 2017 Jun 30.

Longo, Dan L.; Camaschella, Clara (7 May 2015). "Iron-Deficiency Anemia". New England Journal of Medicine. 372 (19): 1832–1843. doi:10.1056/NEJMra1401038. PMID 25946282

Congdon EL, Westerlund A, Algarin C, et al. Iron deficiency in infancy is associated with altered neural correlates of recognition memory at 10 years. J Pediatr. 2012;160:1027– 1033

Falkingham M, Abdelhamid A, Curtis P, et al. The effects of oral iron supplementation on cognition in older children and adults: a systematic review and meta-analysis. Nutr J. 2010;9:4

Powers JM, Buchanan GR. Potential for improved screening, diagnosis and treatment for iron deficiency and iron deficiency anemia in young children. J Pediatr. 2017;188:8– 10

Peyrin-Biroulet, Laurent; Williet, Nicolas; Cacoub, Patrice (December 1, 2015). "Guidelines on the diagnosis and treatment of iron deficiency across indications: a systematic review". The American Journal of Clinical Nutrition. 102 (6): 1585–1594. doi:10.3945/ajcn.114.103366. PMID 26561626

"Soil-transmitted helminth infections". Archived from the original on 2014-02-21. Retrieved 2014-03-05. World Health Organization Fact Sheet No. 366, SoilTransmitted Helminth Infections, updated June 2013

Abdullah K, Birken CS, Maguire JL, et al. Re-evaluation of serum ferritin cut-off values for the diagnosis of iron deficiency in children aged 12-36 months. J Pediatr .2017;188:287–290

Centers for Disease Control Prevention (CDC) (October 11, 2002). "Iron Deficiency – United States, 1999–2000". MMWR. 51 (40): 897–899. PMID 12418542. Archived from the original on May 5, 2012. Retrieved April 21, 2021

DeLoughery TG. Microcytic anemia. N Engl J Med. 2014;371:1324–1331

Ferrara M, Capozzi L, Russo R, et al. Reliability of red blood cell indices and formulas to discriminate between beta thalassemia trait and iron deficiency in children. Hematology. 2010;15(2):112–115

McDonagh MS, Blazina I, Dana T, et al. screening and routine supplementation for iron deficiency anemia: a systematic review. Pediatrics. 2015;135(4):723–733

Powers JM, Buchanan GR. Diagnosis and management of iron deficiency anemia. Hematol Oncol Clin North Am. 2014;28(4):729–74

Jeong WS, Lachance PA. Phytosterols and fatty acids in fig (Ficus carica var. mission) fruit and tree components. Food Chemistry and Toxicology. 2001; 66:278– 281.

Veberic R, Jakopic J, Stampar F. Internal fruit quality of figs (Ficus carica L.) in the Northern Mediterranean Region. Italian Journal of Food Science. 2008; 20(2):255– 262

Vinson JA, Zubik L, Bose P, Samman N, Proch J. Dried fruits: excellent in vitro and in vivo antioxidants. Journal of the American College of Nutrition. 2005; 24(1):44–50

Vinson JA. The functional food properties of figs. Cereal Foods World. 1999; 44(2):82–87

Slatnar A, Klancar U, Stampar F, Veberic R. Effect of drying of figs (Ficus carica L.) on the contents of sugars, organic acids, and phenolic compounds. Journal of Agricultural and Food Chemistry. 2011; 59(21):11696–11702

Veberic R, Colaric M, Stampar F. Phenolic acids and flavonoids of fig fruit (Ficus carica L.) in the northern Mediterranean region. Food Chemistry. 2008; 106(1):153– 157

Solomon A, Golubowicz S, Yablowicz Z, et al. Antioxidant activities and anthocyanin content of fresh fruits of common fig (Ficus carica L.) Journal of Agricultural and Food Chemistry. 2006; 54(20):7717–7723

Iriti M, Faoro F. 2006. Grape phytochemicals: A bouquet of old and new nutraceuticals for human health. Med Hypothesis 67: 833–838

Gujarathi, R., Arora, M., Kulkarni, M., Patwardhan, R., & Kapgate, S. (2022). Evaluating the role of dates compound in iron deficiency anemia in children. International Journal of Health Sciences, 6(S4), 12663–12675. https://doi.org/10.53730/ijhs.v6nS4.12239

Shah Rahul, Pani S, Arora M T, Gujarathi R H. (2023). Effect Of Falgwadi Yoga On Changes In Biochemical Markers Of Iron Deficiency Anaemia. Bull. Env. Pharmacol. Life Sci., Vol 12 [03] February 2023

Shah RH, Meti Rajneesh, Arora MT, Gujarathi Rahul. Anjīra (Ficus carica L) – A food supplement with medicinal benefits. International Journal of Green Pharmacy. Oct-Dec 2020; 14(4):343-347