Main Article Content
Methods: In that case were performed a total clinical systemic examination, computed tomography, magnetic resonance imaging, genetic testing, and optical coherence tomography.
Results: The eye condition was managed by scatter laser treatment, Anti-VEGF injections, anterior chamber paracentesis and trabeculectomy. Non-steroidal eye drops as well as prostaglandin analogues, beta-blockers, and carbonic anhydrase inhibitors have been used as local treatment. Systemic treatment included an intravenous methylprednisolone course, oral corticosteroids, azathioprine, mycophenolate mofetil and total amount of 12 Anti-VEGF injections.
Conclusion: Despite aggressive treatment with oral steroids, immunosuppressants, anti-VEGF injections, there were many exacerbations, and remission was not achieved. As a result, aggressive neovascular glaucoma developed, which led to total blindness in the left eye and legal blindness in the right eye.
Raizada K, Tripathy K. Eales Disease. Treasure Island (FL): StatPearls Publishing; 2023;
Farrar J, J. Hotez P., Junghanss T., Kang G., Lalloo D., J. White N. Manson's Tropical Diseases, Twenty-Third Edition. UK, 2014; 67: 977-978.
Salmon J. Kanski's Clinical. Ophthalmology. UK, 2020; 13: 546-647.
Biswas J, Reesha R, Naryanasamy A, Kulandai L, Madhavan H. Eales' disease - current concepts in diagnosis and management. J Ophthalmic Inflamm Infect. 2013; 3: 11.
Whitcup S, Sen N. Whitcup and Nussenblatt's Uveitis, Fifth Edition. USA, 2022; 28: 351-354.
Sadda S, Sarraf D, Freund K, Hinton D, Schachat A, Wilkinson C, Wiedemann P. Ryan's Retina, Seventh Edition. USA, 2022; 84: 754-1761.
Ishaq M, Niazi M. Usefulness of laser photocoagulation in managing asymptomatic eyes of Eales` disease. J Ayub Med Coll Abbottabad. 2002; 14(4):22-5.
Paroli M. Clinical use of biologics in vasculitis syndromes. Rome, Italy, Biologics. 2012; 6: 371–378.
Cai S, Su G, Li H, Xie B, Luo J. Profiling of human leukocyte antigens in Eales disease and tuberculosis. Int Ophthalmol. 2013; 33(5):475-9.