A Comprehensive Review on Herbal Medicinal Plants for Urinary Tract Infections

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Falakaara Saiyed
Rajesh Maheshwari
Dilsar Gohil
Krupa Joshi
Foram Bhatt


In a ratio of 1:8, urinary tract infections affect both men and women most frequently. People are affected all throughout their lives. Pathogenic bacteria including Escherichia coli, Staphylococcus saprophyticus, Klebsiella pneumoniae, Proteus mirabilis, and fungus like Candida albicans are responsible for UTIs. UTIs can be treated with antibiotics, but that is not the best course of action. Antibiotic usage destroys healthy bacteria, which are vital for a healthy immune system. Antibiotic effectiveness is decreased and resistant bacterial strains are increased by frequent usage of antibiotics. Therefore, it is recommended to take antibiotics sparingly. Natural antimicrobial medicines serve as an accessible and secure alternative treatment for UTIs without raising the danger of antibiotic resistance. Therefore, the current study describes the efficient natural treatments for UTIs.

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Falakaara Saiyed, Rajesh Maheshwari, Dilsar Gohil, Krupa Joshi, & Foram Bhatt. (2023). A Comprehensive Review on Herbal Medicinal Plants for Urinary Tract Infections. Journal of Coastal Life Medicine, 11(2), 348–356. Retrieved from https://jclmm.com/index.php/journal/article/view/1001


Griebling TL. Urologic diseases in America project: trends in resource use for urinary tract infections in men. J Urol, 173:1288‐1294.

Griebling TL. Urologic diseases in America project: trends in resource use for urinary tract infections in women. J Urol. 2005; 173:1281‐1287.

Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Am J Med. 2002; 113: S5‐S13

National Kidney and Urologic Diseases Information Clearing House. Urinary tract infections in adults.

http://www.kidney.niddk.nih.gov/kudiseases/pubs/utiadult /index.htm#Research

Viday, Reddy MD. Urinary tract (kidney and bladder) infections. http://www.drreddy.com/uti.html.

Urinary Tract Infections.


Nicolle L. Best pharmacological practice: urinary tract infections. Expert Opin Pharmacother. 2003; 4:693‐704.

Nicolle LE. Uncomplicated urinary tract infection in adults including uncomplicated pyelonephritis. Urol Clin North Am. 2008; 35(1):1-12.

Lane. Dr, Takhar. SS. Diagnosis and management of urinary tract infection and pyelonephritis. Emergency medicine clinics of North America. 2011; 29(3):539-52.

Salvatore S, Salvatore S, Cattoni E, Siesto G, Serati M, Sorice P, et al. Urinary tract infections in women. European journal of obstetrics, gynecology, and reproductive biology. 2011; 156(2):131-6.

L. Soulsby. Resistance to antimicrobials in humans and animals. Brit. J. Med. 2005; 331:1219-1220.

H. C. Neu. The crisis in antibiotic resistance. Science. 1992; 257: 1064-1073.

World Health Organization (WHO). Traditional medicine – growing needs and potential. WHO Policy Perspectives on Medicine, No. 2; WHO/EDM/2002, WHO:Geneva.

M.M. Cowan. Plant products as antimicrobial agents. Clin. Microbiol. Rev. 1999; 12(4): 564-582.

Basile et al. Antibacterial allelopathic activity of extract from Castanea sativa leaves. Fitoterapia. 2000; 71: 110-116.

Liu Yz, Cao Yg, Ye Jq, Wang Wg, Song Kj, Wang Xl, et al. Immunomodulatory effects of proanthocyanidin A-1 derived in vitro from Rhododendron spiciferum. Fitoterapia. 2010; 81(2):108-114.

Singh I, Gautam Lk, Kaur Ir. Effect of oral cranberry extract (standardized proanthocyanidin-A) in patients with recurrent UTI by pathogenic E. coli: A randomized placebo-controlled clinical research study. Int Urol Nephrol. 2016; 48(9):1379-86.

European Scientific Co-operative for Phytotherapy. Proposal for European Monographs. vol.3. Bevrlidingslaan, Netherlands, ESCOP Secretariat, 1992.

C. Newall, L. Anderson, J. Phillipson. Herbal Medicines: A Guide for Health-care Professionals. (London: Pharmaceutical Press; 1996). 1996; 258-259.

Natural UTI Remedies.


Mark Pedersen, Nutritional Herbology: A Reference Guide (Warsaw, Indiana: Wendell W. Whitman Company,1994). 1994.

M. Blumenthal, W.R. Busse, A. Goldberg et al.(eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines, (Austin American Botanical Council of Boston: Integrative Medicine Communications,1998). 1998; 317.

V. M. Kienholz, B. Kemkes. The antibacterial action of ethereal oils obtained from horseradish root (Cochlearia armoracia L.). Arzneimittel Forsch. 1961; 10:917-918.

Oyelami Oa, Agbakwuru Ea, Adeyemi La, Adedeji Gb. The effectiveness of grapefruit (Citrus paradise) seeds in treating urinary tract infections. J Altern Complement Med. 2005; 11(2):369-71.

Wang H, Luo K, Tan L-Z. p 53-induced Gene 3 Mediates Cell Death Induced by Glutathione Peroxidase 3. The Journal of Biological Chemistry. 2012; 287(20):16890- 16902.

Mansour A, Hariri E, Shelh S, Irani R, Mroueh M. Efficient and Cost-Effective Alternative Treatment for Recurrent Urinary Tract Infections and Interstitial Cystitis in Women: A Two-Case Report. Case Reports in Medicine, 2014; 698758.



Allavi SH, Puri VM, Knabel SJ, Mohtar RH, Whiting RC. Development and validation of a dynamic growth model for Listeria monocytogenesin fluid whole milk. Journal of Food Protection. 2001; 62(2):170-176.

Singh A, And Purohit B. sTooth brushing, oil pulling and tissue regeneration: A review of holistic approaches to oral health. J Ayurveda Integr Med. 2011; 2(2):64-68.

Chaieb K, Hajlaoui H, Zmantar T, Kahla-Nakbi Ab, Rouabhia M, Mahdouani K, Bakhrouf A. The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata (Syzigium aromaticum L. Myrtaceae): A short review. Phytother Res. 2007; 21(6):501-506.

Bukovska A, Cikos S, Juhas S, Il’kova G, Rehak P, Koppel J. Effects of a Combination of Thyme and Oregano Essential Oils on TNBS-Induced Colitis in Mice. Mediators of Inflammation, 2007, 23296

V.E. Schindler, H. Zipp, I. Marth. Comparative clinical investigations of an enzyme glycoside mixture obtained from horseradish roots (Cochlearia armoracia L.). Arzneimittel Forsch. 1961; 10: 919-921.

Urinary Tract Infection Treatment: Goldenseal.

http://EzineArticles.com/?Urinary-TractInfection-Treatment:- Goldenseal&id=528967

Hoffmann D. The New Holistic Herbal, 3rd ed. (Shaftesbury, Dorset, UK: Element, 1990). 1990; 224.

K. Galle, B. Müller-Jakic, A. Proebstle et al. Analytical and pharmacological studies on Mahonia aquifolium. Phytomedicine. 1994; 1:59-62.

S. Foster, V. Tyler. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. (Binghamton, NY: Haworth Herbal Press, 1999). 1999; 43-45.

D.X. Sun, S.N. Abraham, E.H. Beachey. Influence of berberine sulfate on synthesis and expression of pap fimbrial adhesin in uropathogenic Escherichia coli. Antimicrob. Agents. Chemother. 1988; 32: 1274-1277.

D.D. Doan, N.H. Nguyen, H.K. Doan et al. Studies on the individual and combined diuretic effects of four Vietnamese traditional herbal medicines (Zea mayes, Imperata cylindrica, Plantago major and Orthosiphon staminens). J. Ethnopharmacol. 1992;36: 225-231.

Krishnaiah D, Devi T, Bono A, Sarbatly R. Studies on phytochemical constituents of six Malaysian medicinal plants. J Med Plants Res. 2009; 3:67-72.

Karuppiah P, Rajaram S. Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple‐drug resistant clinical pathogens. Asian Pac J Trop Biomed. 2012; 2:597‐ 601.

Sahoo S, Kar DM, Mohapatra S, Rout SP, Dash SK. Antibacterial activity of Hybanthus enneaspermus against selected urinary tract pathogens. Ind J Pharm Sci. 2006; 68:56‐60

Sharma A, Meena S, Barman N. Efficacy of ethyl acetate and ether extract of Terminalia chebula Retz against some human pathogenic strains. Inter J Pharm Tech Res. 2011; 3:4-7.

Joshi B, Lekhak S, Sharma A. Antibacterial property of different medicinal plants: Ocimum sanctum, Cinnamomum zeylanicum, Xanthoxylum armatum and Origanum majorana. Kathmand Univ J Sci Engineer Technol. 2009; 5:143‐150.

Shanmugapriya R, Ushadevi T. In vitro antibacterial and antioxidant activities of Apium graveolens L. seed extracts. Int J Drug Dev Res. 2014; 6:165‐170

Šarić‐Kundalić B, Dobeš C, Klatte‐Asselmeyer V, Saukel J. Ethnobotanical study on medicinal use of wild and cultivated plants in middle, south and west Bosnia and Herzegovina. J Ethnopharmacol. 2010; 131:33‐55.

A.B. Howell, N. Vorsa, A. Der Maderosian. Inhibition of the adherence of P- fimbricated E. coli to uroepithelial – all surfaces by proanthocyanidine extracts from cranberries. New Eng J Med. 1998; 339: 1005-1006.

V.E. Tyler. Herbs of Choice: The therapeutic Use of Phytomedicinals. (New York: Pharmaceutical product press, 1994). 1994; 52-54.

M. Wichtl. Herbal Drugs and Phytopharmaceuticals. (Boca Raton, FL: CRC Press, 1994). 1994; 102-3.

F.E. Hahn, J. Ciak. Berberine. Antibiotics, 3: 577-88.

R.F. Weiss. Herbal Medicine. (Gothenburg, Sweden: Ab Arcanum 1988). 1988; 238-9.

M. Blumenthal, A. Golberg, J. Brinckman. Herbal Medicine: Expanded Commission E Monographs. (Newton, MA: Integrative Medicine Communications,2000). 2000; 218-20.

B. Obertreis, K. Giller, T. Teucher et al. Antiphlogistic effects of Urtica dioica folia extract in comparison to caffeic malic acid. Arzneimittelforschung. 1996; 46: 52-56.

D. Sun, H.S. Courtney, E. H. Beachey. Berberine sulfate blocks adherence of Streptococcus pyogenes to epithelial cells, fibronectin and hexadecane. Antimicrob. Agents. Chemother. 1988; 32: 1370-1373.

M. Blumenthal, W.R. Busse, A. Goldberg et al.(eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines, (Austin American Botanical Council of Boston: Integrative Medicine Communications,1998). 1998; 186-187.

M. Wichtl, N. Bisset (eds). Herbal Drugs and Phytopharmaceuticals. (Stuttgart: Medpharm. Scientific Publishers and Boca Raton, FL: CRC Press, 1994). 1994; 378-381.

D.P. Kamdem, D.A. Gage. Chemical composition of essential oil from the root bark of Sassafras albidum. Planta Med. 1995; 61: 574-575.

Al‐Jiffri O, El‐Sayed Z, Al‐Sharif F. Urinary tract infection with Escherichia coli and antibacterial activity of some plant’s extracts. Int J Microbiol Res. 2011; 2:1-7.

Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care–associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008; 36:309-332.

Abraham G, Varughese S, Thandavan T, et al. chronic kidney disease hotspots in developing countries in South Asia. Clin Kidney J. 2016; 9:135‐141.

Dubey D, Padhy RN. Antibacterial activity of Lantana camara L. against multidrug resistant pathogens from ICU patients of a teaching hospital. J Herb Med. 2013; 3:65‐75